Here David shows,
I. How little he valued the will - will of sinners. There were those that dealt perversely with him, that were peevish and ill-conditioned towards him, that sought advantages against him, and misconstrued all he said and did. Even those that deal most fairly may meet with those that deal perversely. But David regarded it not, for, 1. He knew it was without cause, and that for his love they were his adversaries. The causeless reproach, like the curse causeless, may be easily slighted; it does not hurt us, and therefore should not move us. 2. He could pray, in faith, that they might be ashamed of it; God's dealing favourably with him might make them ashamed to think that they had dealt perversely with him. "Let them be ashamed, that is, let them be brought either to repentance or to ruin." 3. He could go on in the way of his duty, and find comfort in that. "However they deal with me, I will meditate in thy precepts, and entertain myself with them."
II. How much he valued the good-will of saints, and how desirous he was to stand right in their opinion, and keep up his interest in them and communion with them: Let those that fear thee turn to me. He does not mean so much that they might side with him, and take up arms in his cause, as that they might love him, and pray for him, and associate with him. Good men desire the friendship and society of those that are good. Some think it intimates that when David had been guilty of that foul sin in the murder of Uriah, though he was a king, those that feared God grew strange to him and turned from him, for they were ashamed of him; this troubled him, and therefore he prays, Lord, let them turn to me again. He desires especially the company of those that were not only honest, but intelligent, that have known thy testimonies, have good heads as well as good hearts, and whose conversation will be edifying. It is desirable to have an intimacy with such.

Mine eyes fail for thy word,.... Either with looking for the Messiah, the essential Word, that was to be, and afterwards was made flesh, and dwelt among men; or for the fulfilment of the word of promise, on which he was made to hope; but that being deferred; and he believing in hope against hope, and looking out continually till it was accomplished, his eyes grew weary, and failed him, and he was just ready to give up all expectation of it; see Psa 77:8;

saying, when wilt thou comfort me? The people of God are sometimes very disconsolate, and need comforting, through the prevalence of sin, the power of Satan's temptations, the hidings of God's face, and a variety of afflictions; when they apply to God for comfort, who only can comfort them, and who has his set times to do it; but they are apt to think it long, and inquire, as David here, when it will be.