In these verses we see the work going on in the appointed order. The fourth angel poured out his vial, and that fell upon the sun; that is, say some, upon some eminent prince of the popish communion, who should renounce their false religion a little while before his utter downfall; and some expect it will be the German emperor. And now what will be the consequence of this? That sun which before cherished them with warm and benign influences shall now grow hot against these idolaters, and shall scorch them. Princes shall use their power and authority to suppress them, which yet will be so far from bringing them to repentance, that it will cause them to curse God and their king, and look upward, throwing out their blasphemous speeches against the God of heaven; they will be hardened to their ruin. The fifth angel poured out his vial, Rev 16:10. And observe, 1. Where this fell - upon the seat of the beast, upon Rome itself, the mystical Babylon, the head of the antichristian empire. 2. What effect it had there: The whole kingdom of the beast was full of darkness and distress. That very city which was the seat of their policy, the source of all their learning, and all their knowledge, and all their pomp and pleasure, now becomes a source of darkness, and pain, and anguish. Darkness was one of the plagues of Egypt, and it is opposed to lustre and honour, and so forebodes the contempt and scorn to which the antichristian interest should be exposed. Darkness is opposed to wisdom and penetration, and forbodes the confusion and folly which the idolaters should discover at that time. It is opposed to pleasure and joy, and so signifies their anguish and vexation of Spirit, when their calamities thus came upon them.

The seat of the beast - Επι τον θρονον του θηριου· Upon the throne of the wild beast. The regal family was smitten by the fourth vial; they did not repent: then the fifth angel pours out his vial on the throne of the wild beast, or antichristian idolatrous power.
Was full of darkness - Confusion, dismay, and distress.

And blasphemed the God of heaven,.... Who made it, and dwells in it, and from whence wrath is revealed, and comes upon the seat of the beast, upon the kingdom of antichrist, and the subjects of that kingdom; they will curse him who is of right their King, and their God, and look upwards to heaven, where he is, Isa 8:21 and this,

because of their pains and their sores: see Rev 16:2 the inward frettings and distresses of their minds, the gallings and gnawings of their consciences, the horror and terror of their souls, and their fearful looking for of judgment, which the present face of things upon antichrist will bring upon them; just as the Egyptians, in the time of their darkness, were distressed with internal guilt, and black horror of mind, and with evil spirits, which were sent among them, and haunted them during that season; see Psa 78:49 and repented not of their deeds; their antichristian works of darkness; see Rev 9:20.

angel--omitted by A, B, C, Vulgate, and Syriac. But Coptic and ANDREAS support it.

seat--Greek, "throne of the beast": set up in arrogant mimicry of God's throne; the dragon gave his throne to the beast (Rev 13:2).

darkness--parallel to the Egyptian plague of darkness, Pharaoh being the type of Antichrist (compare Notes, see on Rev 15:2-3; compare the fifth trumpet, Rev 9:2).

gnawed their tongues for pain--Greek, "owing to the pain" occasioned by the previous plagues, rendered more appalling by the darkness. Or, as "gnashing of teeth" is one of the accompaniments of hell, so this "gnawing of their tongues" is through rage at the baffling of their hopes and the overthrow of their kingdom. They meditate revenge and are unable to effect it; hence their frenzy [GROTIUS]. Those in anguish, mental and bodily, bite their lips and tongues.